| International |
Theta-Burst Transcranial Magnetic Stimulation for PTSD |
United States, 2019 |
50 |
10 days of sham-controlled iTBS, followed by 10 unblinded sessions. Analysis from both participants and clinicians were recorded. |
Depression decreased outside of sham treatments. Significant positive changes found within PTSD-related symptoms, depression, social and occupational function. Concluded that iTBS appears to be a promising new treatment for PTSD. |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02090179/full |
| International |
Repetitive Transcranial Magnetic Stimulation for Functional Tremor: A Random Double-Blind, Controlled Study |
France, 2019 |
33 |
2 month duration of active/sham repetitive TMS therapy. |
Depression and Anxiety were reported to decrease in active trials when compared to sham. TMS continued to decrease these symptoms over a longer period of time (up to 12 months). |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01958401/full |
| International |
Online Repetitive Transcranial Magnetic Stimulation During Working Memory In Younger and Older Adults: a randomized within-subject comparison |
United States, 2019 |
47 |
Over a few weeks with only active TMS therapy applied. |
More studies needed into TMS in developing memory enhancement, with the likelihood that it will provide benefits to the patients. |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01915761/full |
| International |
Effects of High-Frequency Neuronavigated Repetitive Transcranial Magnetic Stimulation in Fibromyalgia Syndrome: a Double-Blinded, Randomized Controlled Study |
United States, 2020 |
20 |
20 Participants split into 2 groups, one receiving TMS therapy, and the other receiving sham treatment. |
Fibromyalgia and visual analog-scale stiffness improved in the TMS group. Further studies needed to conclude about long-term effects of TMS. |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02139190/full |
| International |
Repetitive TMS in Alcohol Dependence: study protocol of a randomized controlled clinical trial of efficacy and working mechanisms |
Netherlands, 2019 |
80 |
A randomized, single blind, controlled trial. 10 sessions of either active or sham treatments. |
TMS was shown to help with alcohol dependency, with an improvement in symptoms of anxiety and depression. |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01913528/full |
| International |
Efficacy and Safety of Deep Transcranial Magnetic Stimulation for Obsessive-Compulsive Disorder: a Prospective Multicenter Randomized Double-Blind Placebo-Controlled Trial |
United States, 2019 |
99 |
Two groups of either active or sham treatment over the course of 6 weeks. |
There was a significant reduction in symptoms according to the Yale-Brown Obsessive Compulsive Scale in the group with active treatment when compared to the sham treatment. In a 1-month follow up, 45.2% of patients had a positive response in the active treatment group when compared to the sham group (11.1%). |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01956554/full |
| International |
Effect of Repetitive Transcranial Magnetic Stimulation on Treatment-Resistant Major Depression in US Veterans: a Randomized Clinical Trial – |
United States, 2018 |
164 |
Double-blind, sham-controlled randomized trial over the course of 4 years. Up to 30 sessions for each participant, being allocated either a sham or genuine treatment. 81 had genuine treatment. |
39% of veterans showed a remission in depressive symptoms. |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01991293/full |
| International |
Effects of Repetitive Transcranial Magnetic Stimulation on Improvement of Mental Health and Clinical Parameters in Depressed Hemodialysis Patients: a Pilot Study |
|
14 |
Active and sham treatments over the course of 4 weeks. |
The TMS treatment group showed a significant improvement in the Hamilton Depression Scale when compared to the sham group. Anxiety and Somatization symptoms were also reduced in the TMS group. |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02140966/full |
| International |
Pain Trajectories of Dorsomedial Prefrontal Intermittent Theta Burst Stimulation Versus Sham Treatment in Depression |
United States, 2020 |
36 |
Randomized, blind trial with active and sham treatments. |
Pain reduction was found in the TMS group when compared to the sham group. This was constant throughout the trial. |
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02196046/full |
| UK |
Repetitive Transcranial Magnetic Stimulation for Depression: outcomes in a United Kingdom Clinical Practice |
United Kingdom, 2015 to 2017 |
73 |
Overview of rTMS therapy conducted between 2015 and 2017 |
The NHS show a similar trend found internationally – there is a significant improvement in depression and anxiety symptoms, according to the Hamilton Depression Scale. The study concludes that the NHS could make financial savings alongside patient improvement by investing in rTMS. |
https://pubmed.ncbi.nlm.nih.gov/30931656/ |
| UK |
The London Psychiatry Centre Recovery Rates for Treatment-Resistant Depression with rTMS |
United Kingdom, 2020 |
252 |
252 participants conducted during a survey. |
61% of patients went into remission, 59% of women and 62% of men had been deemed as ‘recovered’. |
https://www.psychiatrycentre.co.uk/repetitive-transcranial-magnetic-stimulation-rtms-clinic/ |
| UK |
Connectivity Guided Theta Burst Transcranial Magnetic Stimulation versus Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant moderate to severe Depression: study protocol for a randomised double-blind controlled trial (BRIGHTMIND) |
United Kingdom, 2020 |
368 |
368 participants in a double-blind trial, receiving one of two rTMS treatments. |
Both kinds of rTMS treatment were deemed effective in treating depression. Further studies into rTMS has also been suggested. |
https://bmjopen.bmj.com/content/10/7/e038430 |
